Reagents that inhibit fibronectin matrix assembly of cultured cells also inhibit lung branching morphogenesis in vitro. Implications for lung development, injury, and repair.
نویسندگان
چکیده
منابع مشابه
Potential role of RGD-binding integrins in mammalian lung branching morphogenesis.
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Fibronectin (FN) is one of the essential component of the extra cellular matrix and their important role is as regulator of cellular activities and also fibronectin is an important scaffold for maintaining tissue. Fibronectin conformational changes expose additional binding sites that participate in fibril formation and in conversion of fibrils into a stabilized, insoluble form. In fact fibrone...
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ورودعنوان ژورنال:
- Chest
دوره 99 3 Suppl شماره
صفحات -
تاریخ انتشار 1991